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Home > products > Cosmetic Plant Extracts > Organic Cosmetic Plant Extracts Anti Tumor 78287-27-1 Camptotheca Extract

Organic Cosmetic Plant Extracts Anti Tumor 78287-27-1 Camptotheca Extract

Product Details

Place of Origin: Shandong.China

Brand Name: VNI

Certification: Kosher Halal ISO

Model Number: Organic Plant Extracts

Payment & Shipping Terms

Minimum Order Quantity: 1kg

Price: $1-$50

Packaging Details: 25kg/drum

Delivery Time: Sample Order 1-3work days Batch Order 3-5 work days

Payment Terms: L/C, T/T, Western Union

Supply Ability: 50000kg/Year

Get Best Price
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Organic Cosmetic Plant Extracts

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Cosmetic Plant Extracts Anti Tumor

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78287-27-1

Product Name:
Camptotheca Extract
Botanical Source:
(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
Specification:
98% Camptothecin
Appearance:
Light Yellow Crystalline Powder
Test Method:
HPLC
Part Used:
Leaf
CAS NO.:
78287-27-1
Extraction Type:
Solvent Extraction
Product Name:
Camptotheca Extract
Botanical Source:
(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
Specification:
98% Camptothecin
Appearance:
Light Yellow Crystalline Powder
Test Method:
HPLC
Part Used:
Leaf
CAS NO.:
78287-27-1
Extraction Type:
Solvent Extraction
Organic Cosmetic Plant Extracts Anti Tumor 78287-27-1 Camptotheca Extract

ISO Certified Camptotheca Extract 98% Camptothecin HPLC C22H20N2O4

 

 

Description:

 

Camptothecin (CPT) is a cytotoxic quino line alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E.
 
Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the bark and stem of Camptotheca
 
acuminata (Camptotheca, Happy tree), a tree native to China used as a cancer treatment in Traditional Chinese Medicine. CPT showed
 
remarkable anticancer activity in preliminary clinical trials but also low solubility and (high) adverse drug reaction. Because of these disadvantages
 
synthetic and medicinal chemists have developed numerous syntheses of Camptothecin and various derivatives to increase the benefits of the
 
chemical, with good results. Two CPT analogues have been approved and are used in cancer chemotherapy today, topotecan and irinotecan.
 

 

Specifications:

 

Product Name Camptotheca Extract
Appearance Light yellow crystalline powder
Speicification 98% Camptothecin
Molecular Weight 376.40
Molecular Formula C22H20N2O4
Shelf life 2 years
HS Code 2932999099
Function Anti tumor effect.

 

 

Benefits:

 

 

1. Camptothecin and its derivatives are unique in their ability to inhibit DNA Topoisomerase I, by stabilizing a covalent reaction intermediate

 

termed the cleavable complex which ultimately causes tumor cell death.


2. In clinical it is widely believed that camptothecin analogs exhibited remarkable anti-tumour and anti-leukaemia activity. Topoisomerase is a

 

basilic enzyme in the process of DNA replication, it is responsible for the winding / unwinding of the supercoiled DNA composing the

 

chromosomes. If the chromosomes cannot be unwound, transcription of DNA message cannot occur and the protein cannot be synthesized, it

 

ultimately causes cell death.


3. Application of camptothecin in clinic is limited due to serious side effects and poor water-solubility.


4. At present, some camptothecin analogs,either semi-synthetic or synthetic drug based on camptothecin, have been applied cancerous therapy

 

such as topotecan and irinotecan while others have been obtained satisfying curative effects in clinic.

 

 

Application:

 

1. Camptothecin can make changes in skin epidermal keratinization process.

2. Camptothecin is used for anti-cancer, anti-virus, immune inhibition, anti early pregnancy.

3. Camptothecin has the function of treatment of gastric cancer, liver cancer, head and neck cancer and leukemia,with fewer side effects than
 
camptothecine.

 

 

Our Company

 

Qingdao Vital Nutraceutical Ingredients BioScience Co.,Ltd (VNI)has being specialists on: Study how natural plant ingredients benefit human

 

health, R & D the natural extraction. VNI supplies the qualified and innovative natural plant extracts, natural nutraceuticals OEM Services as well

 

as powerful technique supports and excellent service Since the last century phytotherapy has bocome a scientific discipline; this is why VNI

 

believes in the constant search for natural ingredients, aiming at new scientific and technological attainments.[Value]


Respect for nature, respect for people


Think Green, Live Green


[Mission)]


Supply health products, with an innovative approach for the benefitof mankind and the due respect for nature.Enterprise Spirits: Good Quality,

 

Valuable Service and HighEfficiency.

 

 

 

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FAQ


1. Sample
50-100g free sample could offered to you to test the quality.


2. MOQ
IKG pack in aluminum foil bag.


3. Common Package
25kgs/Drum, 20kgs/Carton, 1kg/Bag etc


4. Delivery Leadtime
It is about 2-3day after payment or order confirmed.


5.Payment
Payment could be done by T/T, Western Union, Paypal, LC or Banks indomestic.


6. Discount
Price is determined By Quantity, large quantity with lower price.

 

Yellow Brown to white powder